PCORI is a nonprofit, nongovernmental organization located in Washington, DC whose mandate is to improve the quality and relevance of evidence available to help patients, caregivers, clinicians, employers, insurers, and policy makers make informed health decisions. Congress authorized its funding through the Patient Protection and Affordable Care Act of 2010.
PCORI provides support for comparative clinical effectiveness research (CER) and Patient-Centered Outcomes Research (PCOR). CERs are used to determine the healthcare options available to patients and their caretakers, and under what circumstances. The PCOR framework is utilized where the research questions focus on concerns most relevant to patients, caregivers, clinicians, and other healthcare stakeholders, and the researchers involve these stakeholders in the research process.