Methods: The present study involved secondary data analysis from CHOICES Plus, a randomized clinical trial to test the efficacy of a motivational interviewing-based intervention on reducing the risk of alcohol-exposed pregnancy (AEP) and tobacco-exposed pregnancy (TEP). Women were recruited from 12 primary care clinics in a large Texas public healthcare system. Participants were women who were fertile, not pregnant, aged 18–44 years, drinking more than three drinks per day or more than seven drinks per week, sexually active, and not using effective contraception. Women at-risk for AEP were randomized to CHOICES Plus (n=131) or Brief Advice (n=130). The current study examined abstinence self-efficacy for alcohol as a mediator of the CHOICES Plus intervention on reductions in depression and anxiety. Specifically, this study, using SPSS 26 PROCESS macro (Hayes, 2018), examined indirect paths from intervention condition to abstinence self-efficacy for alcohol at 3-months to depression and anxiety at 9-months . Abstinence self-efficacy for alcohol was measured using the Brief Situational Confidence Questionnaire. Depression and generalized anxiety were measured using the Brief Symptom Inventory-18.
Results: There was not a direct effect of the CHOICES Plus intervention on reductions of depression or anxiety at 9-months. However, as hypothesized, the study found an indirect association with decreased depression at 9-months through abstinence self-efficacy for alcohol at 3-months (indirect effect = -.0643, 95% CI = -.1347, -.0148) and an indirect association of decreased anxiety at 9-months through abstinence self-efficacy for alcohol at 3-months (indirect effect = -.0511, 95% CI = -.1105, -.0101). The intervention was associated with an increase in abstinence self-efficacy for alcohol at 3-months (b=.42, t=3.23, p<.01), which was in turn associated with decreased depression (b=-.15, t=-3.42, p=<.001) and anxiety (b=-.12, t=-2.86, p=<.01) at 9 months.
Conclusions and Implications: Increasing confidence to change a behavior can have the additional benefit of reducing psychological distress. Since alcohol and other substance use disorders are highly comorbid with depression and anxiety, the present study indicates that motivational interviewing-based interventions may be especially useful and practical in addressing internalizing disorders.