Methods: With the data from a study focused on Black, African American, Hispanic, and Latino/e young adults (ages 19-28) living with HIV in New York City and Newark, NJ (N = 244), we ran hierarchical OLS regressions to explore the factors associated with depression severity and assess the moderation effect of HIV treatment engagement on the relationship between depression and HIV-related stigma, using viral load suppression status as a proxy for HIV care engagement. Participants were recruited using purposive sampling methods, and data was collected from 2021 to May 2023.
Results: The results demonstrated that 1) higher levels of HIV stigma were associated with more severe depression (r = .352, p < 0.001), 2) the level of HIV stigma did not differ for treatment-engaged and non-treatment-engaged individuals (r = 0.07, p = 0.260), 3) treatment engagement alone did not predict depression severity (r = -0.04, p = 0.532), and lastly, 4) results indicated a statistically significant interaction effect associated with HIV stigma and care engagement (B = 0.30, SE = 0.015, p = 0.049; R² = 0.21).
Conclusions and Implications: YEA-LWH more engaged in care experienced less severe depression in the face of HIV stigma, while those who were less engaged were more vulnerable to stigma’s adverse effects on mental health via depression. Consistent with previous literature, HIV stigma was significantly associated with depression severity. The significant moderation effect indicates that the relationship between HIV stigma and depression severity was not the same for everyone. Instead, it depends on whether individuals are actively engaged in managing their HIV. These novel findings demonstrate the importance of multicomponent approaches to treatment for Black and Latine YEA-LWH. The nuanced relationship between depression, HIV-related stigma, and treatment engagement revealed by this study provides critical information as to how and where to intervene for Black and Latine YEA-LWH to better address the impacts of HIV stigma on depression as a mental health outcome.