Methods. Nine electronic databases were searched. Two reviewers independently screened studies, extracted data, and assessed evidence quality. We used robust variance estimation in meta-regression for synthesizing effect sizes and moderator analyses. Sensitivity analysis and publication bias assessment were also performed.
Results. In total, 113 studies were included in the review. The overall between-group effect size (Hedge’s g) was .25 (95% CI= .19, .30). Effect sizes for TBIs’ effects on alcohol use, drug use, unspecified/multiple substance use, substance use consequences were .25 (95% CI=.18, .31), .35 (95% CI=.15, .55), .22 (95% CI= -.16, .60), and .16 (95% CI=.04, .28), respectively. Moderator analysis showed that TBIs with human contact had a larger effect than TBIs without human contact (b=.14, SE=.06, t=2.21, p<.050).
Conclusion and Implications. TBIs are effective for improving substance use and related consequences among YA/CS and TBIs with some human contact might have a greater effect than TBIs solely delivered by technology. Overall, this study highlights the need for continued monitoring of technology-driven interventions for substance use,and can provide valuable insights into ways that evolving technology can be developed for substance use interventions.