Presidential Plenary [presented in person]

HOLDEN THORP

Holden Thorp became Editor-in-Chief of the Science family of journals in October 2019. He came to Science from Washington University, where he was provost from 2013 to 2019 and professor from 2013 to 2023. He is currently a professor of chemistry and medicine at George Washington University and on leave to serve as the Editor-in-Chief at Science. Thorp joined Washington University after spending three decades at the University of North Carolina at Chapel Hill (UNC), where he served as the 10th chancellor from 2008 through 2013. Thorp earned a bachelor of science degree from UNC, a doctorate in chemistry from the California Institute of Technology, and completed postdoctoral work at Yale University. He holds honorary degrees from the Olin College of Engineering, Hofstra University, and North Carolina Wesleyan College and is a fellow of the American Academy of Arts and Sciences, the National Academy of Inventors, and the American Association for the Advancement of Science.

Thorp cofounded Viamet Pharmaceuticals, which developed VIVJOA (oteseconazole), now approved by the FDA and marketed by Mycovia Pharmaceuticals. Thorp is a venture partner at Hatteras Venture Partners, a consultant to Ancora, Huron, and Urban Impact Advisors, and is on the board of directors of PBS and Saint Louis University. He serves on the scientifi c advisory boards of the Yale School of Medicine and the Underwriters' Laboratories Research Institutes. In 2023, STAT named Thorp to its STATUS list of top leaders in the life sciences. In 2025, he was given the Donald A. B. Lindberg Award for Distinguished Health Communications by the Friends of the National Library of Medicine.

KEISHA LANCE BOTTOMS

Mayor of Atlanta (2018-2022); Director of the White House Office of Public Engagement (2022-2023)

Keisha Lance Bottoms has served as Senior Advisor to President Joe Biden, leading the transformation of the White House Office of Public Engagement, and serving as an advisor, liaison, and media surrogate for President Joe Biden. While serving in the White House, Keisha led engagement strategy, crafted messaging, and advised the President on matters related to millions of diverse stakeholders across America, including CEOs, African-Americans, LGBTQ +, labor unions, AAPI, Latinos, and the disability community. Keisha helped elevate the President's poll numbers by nearly eight points during her tenure.

Before joining the White House, Keisha worked with CNN as a Political Commentator, based in Atlanta, Georgia, where she served as the 60th Mayor. She is a visionary leader in bringing equitable outcomes to the forefront of government and commerce. Keisha became the first Mayor in Atlanta's history to have served in all three branches of government, having previously served as a Judge and a City Council member. As Mayor, she committed herself to realizing her vision of "One Atlanta" an affordable, resilient, and equitable Atlanta.

Sworn in on January 2, 2018, Keisha served as Mayor during one of the most challenging times in the history of Atlanta. In the midst of a global pandemic and a racial justice movement, Keisha became a leading spokesperson regarding the challenges and opportunities facing cities and leaders across America.

While navigating these unprecedented challenges, the Bottoms Administration was able to remain focused on the resilience of Atlanta, negotiating and closing the largest real estate transaction in the history of Atlanta, and one of the largest in the Southeast United States, delivering millions of dollars in community benefits to people across the city.

Keisha took proactive measures to deal with the impact of the COVID-19 pandemic on the City and its agencies. As a result, during one of the worst economic downturns the world has ever faced, the Bottoms Administration delivered four years of balanced budgets, without resorting to property tax increases, layoffs, or furloughs of City employees. At the conclusion of her term, Atlanta's reserves remained at a near-high of $181M, far exceeding the requirements of the City Charter.

Shaped by a childhood and professional career that highlighted the inequalities amongst Americans, Keisha led her Administration in undertaking several major initiatives that would seek to eradicate systemic issues facing Atlanta, while creating a model for all cities to follow.