Method: Seventy-nine primarily Caucasian young adults were randomly assigned to MBRP (n = 44) or TAU (n =35). Individuals assigned to MBRP received eight additional mindfulness sessions and those assigned to TAU received an equal amount of additional 12-step/self-help. The eight MBRP sessions were administered twice per week (90 min each). All participants were followed-up bi-monthly over the course of 6 months assessing self-reported measures of stress, craving, and substance use. Bi-linear spine structural equation models were used to assess intervention effects during the treatment and post-treatment phase.
Results: At treatment completion young adults receiving MBRP had lower substance use (d = -.58), craving (d = -.58), and stress (d = -.77). These results were maintained at study completion with diverging trajectories between MBRP and TAU groups manifesting effect sizes ranging from small (Craving; d = -.28) to rather large (substance use: d = -1.1; stress: d = -1.3). Reduced stress during treatment partially mediated observed outcome differences between MBRP and TAU for substance use (βindirect = -.45 [-.79, -.11]).
Conclusions: This is the first study to provide support for changes in stress as an active mechanism contributing to lower substance use. Overall, findings suggest that MBRP is an appropriate and integrative therapy designed to reduce stress, negative emotion, and substance use among a sample of marginalized young adults.